| Major Employers in Galveston | No. of Employees | |
| 1 | University of Texas Medical Branch | 9000 |
| 2 | American National Insurance Company | 1600 |
| 3 | Galveston Independent School District | 1361 |
| 4 | Landry's Restaurants * | 1300 |
| 5 | Moody Gardens | 922 |
| 6 | City of Galveston | 700 |
| 7 | Fertitta Hospitality ** | 566 |
| 8 | Galveston College | 543 |
| 9 | County of Galveston | 460 |
| 10 | Texas A&M University at Galveston | 397 |
| 11 | U.S. Army Corps of Engineers | 390-400 |
| * | Businesses included: Landry's Seafood, Joe's Crab Shack (two locations), Fish Tales, Willie G's, Rainforest Cafe, Cadillac Mexican Restaurant, Fisherman's Wharf, Fuddruckers, and Landry's Oyster Bar | |
| ** | Businesses included: San Luis Resort & Conference Center, Hilton Resort, Holiday Inn, IHOP | |
| Source: Galveston Economic Development Partnership, 2003 | ||